中国计量大学硕士生导师信息表

基本信息

姓名: 卢秀莲 性别: 学位: 博士
职称: 教授 一级学科: 生物学 二级学科: 生物化学与分子生物学
二级学院: 生命科学学院 一级学科2: 化学 二级学科2: 无机化学
研究方向: 过渡金属配合物的设计、合成、谱学性质研究 过渡金属配合物与DNA的作用机制、生物活性研究 过渡金属配合物的结构与催化性能研究 办公地点: 格致北楼608室
办公电话: 0571-87676268 移动电话: 13777806506 Email: luxiulian@cjlu.edu.cn

在研课题

1、氨基酸-钌有机化合物的合成、结构与性质研究(00049),教育部留学回国人员启动项目,3万, 负责人
2、氨基酸-单茂钌六甲苯基化合物的合成和表征,人事部留学回国人员择优资助项目,3万,负责人

获奖情况

 

近期发表的主要成果

发表论文30多篇,其中SCI收录论文20多篇,作为第一发明人,获得授权发明专利2项,参编教材《药物化学》(浙江大学出版社)一本。
发表部分代表性SCI论文(通讯作者打*号):
[1] Nong, Ping-Sheng, Yi-Feng Zhou, Li-Hong Huang, Ji-Dong Lou, Xiao-Hong Chen,), Xiu Lian Lu*. Syntheses , Charcterization, and structures of two (Arene)Ru(II) complexes containing amino acids. Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2012, 42(3):313-316.
[2] Ji-Dong, Lou,; Fang Lin; Xiu Lian Lu,; Qiang Wang,; Xiao-Nan Zou. A Facile Procedure for the Conversion of Oximes to Ketones and Aldehydes by the Use of Jones Reagent Adsorbed on Kieselguhr Reagent。Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2012, 42(2):282-284.
[3] Juan Yan, Xiu Lian Lu*, Ji-Dong Lou, Lin Zhang, Ping-Sheng Nong, Yun-Long Feng, Min Gao, Juan-Juan Yang. Syntheses , Charcterization, and structures of two (Arene)Ru(II) complexes containing amino acids. Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2011, 41:26 -30.
[4] Xiu Lian Lu*, Lin Zhang, Ji-Dong Lou, Juan Yan, Ping-Sheng Nong, Xiao-Hong Chen, Juan-Juan Yang, Min Gao. Synthesis, Characterization and DNA-binding studies of two cyclopentadienyl ruthenium(II) complexes with amino acid ligands.Transition Metal Chemistry, 2010, 35: 513 – 519.
[5] Ji-Dong Lou, Xiu Lian Lu, Aizen J. Marrogi, Feng Li, Chun-Ling Gao, Xiaoping Yu. A first example of a reaction under viscous conditions: oxidation of solid benzoins with manganese dioxide. Monatsh Chem., 2008, 139, 609 – 611. 
[6] Ji-Dong Lou, Juan Yan, Lin Zhang, Li Li, Negin Vatanian, Xiu Lian Lu, Xiaoping Yu. Selective Oxidation of a-Hydroxy Ketones to a-Diketones with Chromium Trioxide Supported on Kieselghur Reagent. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2008, 38,373 –375. 
[7] Ji-Dong Lou, Juan Yan, Lin Zhang, Li Li, Negin Vatanian, Xiu Lian Lu,Xiaoping Yu. Jones Reagent Supported on Aluminum Silicate: A New Reagent for Oxidation of Alcohols. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2008, 38,370 – 372. 
[8] Xiu Lian Lu, T. D. McGrath, F. Gordon A. Stone*. Synthesis and reactivity of 10 and 12-vertex cobalt-monocarborane anions containing multiple metal centers. Organometallics, 2006, 25, 2590-2598. 
[9] Xiu Lian Lu, Thomas D. McGrath, and F. Gordon A. Stone*.  Synthesis of the manganese-monocarbollides dianion [1-NHBut—2,2,2-(CO)3-closo-2,1-MnCB10H10]2-: Reactions with transition metal cations. Inorganica Chimica Acta 2006,359,2665-2673. 
[10] Xiu Lian Lu, Xiao-Ping Yu, Ji-Dong Lou. Recent Advences in dppf-Containing (Cp/Cp*)Ru and (Arene)Ru(II) Complexes:Structure, Reactivity, Catalysis and Electrochemistry (2000-2005). Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2006, 36,733 – 745.
[11] Xiu Lian Lu, Weng Kee Leong, Lai Yoong Goh *, Tzi Sum Andy Hor, Jagadese J. vittal *. Crystal structures and Characterizations of (Nitrato-O)(Nitrato-O,O′)(η6-Hexamethylbenzene) Ruthenium(II) and Di(Trifluoroacetato-O)-(H2O-O)(η6-Hexamethylbenzene) Ruthenium(II). Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry 2005, 35, 10, 743 - 746. 
[12] Shaowu Du, John C. Jeffery, Jason A. Kautz, Xiu Lian Lu, Thomas D. McGrath, Thomas A. Miller, T. Riis-Johannessen, and F. Gordon A. Stone*. Reactions of the Dianion [1,1,1-(CO)3-2-Ph-closo-1,2-MnCB9H9]2- with Transition-Metal Cations: Facile Insertion and Then Excursion of Cluster Vertexes. Inorganic Chemistry 2005, 44(8), 2815-2825. 
[13] Xiu Lian Lu, Weng Kee Leong, T. S. Andy Hor*, Lai Yoong Goh*. Supramolecular structures in [Ag(dppf)]   complexes  [dppf = 1,1'-bis(diphenylphosphanyl)ferrocene] stabilized by coordinatively versatile trifluoroacetate (TFA) ligands. European Journal of Inorganic Chemistry 2004, 12, 2504-2513.
[14] Xiu Lian Lu, Jagadese J. Vittal, Edward R. T. Tiekink, Lai Yoong Goh*, T. S. Andy Hor*. Chloride substitution of [CpRu(dppf)Cl] with sulfur-containing ligands. Journal of Organometallic Chemistry 2004, 689(9), 1444-1451.  
[15] Xiu Lian Lu, Jagadese J. Vittal, Edward R. T. Tiekink, G. K. Tan, Seah Ling Kuan, Lai Yoong Goh*, T. S. Andy Hor*. Comparative reactivity studies of dppf-containing  CpRu(II) and (C6Me6)Ru(II) complexes towards different donor ligands (dppf = 1,1'-  bis(diphenylphosphino)ferrocene). Journal of Organometallic Chemistry 2004, 689 (11), 1978-1990.  
[16] Xiu Lian Lu, Weng Kee Leong, T. S. Andy Hor*, Lai Yoong Goh*. Coordination polymers and supramolecular structures in Ag(I)triflate-dppf sysmtems (dppf = 1,1'-bis(diphenylphosphino)ferrocene). Journal of Organometallic Chemistry 2004, 689(10), 1746-1756. 
[17] Mitsuhiro Hata, Jason A. Kautz, Xiu Lian Lu, Thomas D. McGrath, and F. Gordon A. Stone*. Revisiting [Mn(CO)3(7,8-C2B9H11)], the dicarbollide analogue of [(C5H5)Mn(CO)3]:  reactivity  studies leading to boron-atom functionalization. Organometallics 2004, 23(15), 3590-3602.  
[18] Xiu Lian Lu,  Sin Yee Ng,  Jagadese J. Vittal , Geok  Kheng Tan , Lai Yoong Goh*, T. S. Andy Hor*.  Structural dynamics and ligand mobility in carboxylate and dithiocarbamate complexes of Ru(II)  containing 1,1'-bis- (diphenylphosphino)ferrocene (dppf). Journal of Organometallic Chemistry 2003, 688(1-2), 100-111. 
[19] Shaowu Du, Bruce E. Hodson, Peng Lei, Xiu Lian Lu, Thomas D. McGrath, and F. Gordon A. Stone*. Metal complexes of monocarbon carboranes: A neglected area of study? Abstracts of Papers of The American Chemical Society 229, 2005, U971-971 071-INOR Part 1, San Diego, CA, USA, March 13-17. 
发表的国际论文:
[20] Mitsuhiro Hata, Jason A. Kautz, Xiu Lian Lu*, Thomas D. McGrath, and F. Gordon A. Stone. Reactivity of [PPN][3,3,3-(CO)3-1,2-Me2-closo-3,1,2-MnC2B9H9] and its derivatives with electrophiles. BORON IN THE AMERICAS IX, San Marcos, Texas, USA, May 19-23, 2004.
[21] Shaowu Du, Bruce Hodson, Jason Kautz, Xiu Lian Lu(卢秀莲), Thomas McGrath*, F. Gordon A. Stone. Building Butterflies on a rhenium-monocarborane substrate, BORON IN THE AMERICAS IX, San Marcos, Texas, USA, May 19-23, 2004.
[22] Xiu Lian Lu, G. K. Tan, Weng Kee Leong, T. S. Andy Hor *, Lai Yoong Goh*. Structural diversity of Ag(I) complexes containing 1,1-bis(diphenylphosphino)ferrocene as ligand, XXth International Conference on Organometallic Chemistry, July 7-12, 2002, Corfu, Greece.
[23] Lai Yong Goh*, Xiu Lian Lu, Jagadese J. Vittal, T. S. Andy Hor*. Synthesis, characterization and X-ray structures of some cyclopentadienylruthenium complexes containing dppf ligand. 2nd Singapore International Chemical   Conference, Dec. 18-25, 2001, Singapore.
[24] Xiu Lian Lu, Sin Yee Ng, Lai Yoong Goh*, Weng Kee Leong, Jagadese J. Vittal, T. S. Andy Hor*. Carboxylate and thiocarboxylate complexes of Ru(II) and Ag(I) containing dppf. 2nd Singapore International Chemical Conference, Dec. 18-25, 2001, Singapore.
[25] Xiu Lian Lu *, Ji-Dong Lou,Jian Ge, Qing-Li Meng, Lin Zhang, Juan Yan.  Synthesis, Characterization and antitumor activity of some organoruthenium(II) complexes conatining amino acids. 10th International Symposium for Chinese Organic Chemists and 7th International Symposium for Chinese Inorganic Chemists. July 27th-July 31th, 2008. China, Shanghai.

主持完成的科研项目

序号 项  目  名  称 项目编号 项目来源 起止日期 科研经费
(万元) 本人负责内容
1 天然抗癌药咖啡酸苯乙醇酯绿色化学合成关键技术研究与开发 2008C11045 浙江省科技厅重大专项 2008.1 — 2010.12 100万 负责人
2 PEG修饰氯硝柳胺衍生物的合成及灭福寿螺效果研究 01002-123-080050 浙江省钱江人才计划 2008.12 — 2011.12 5万 负责人
3 某些含氨基酸的钌环戊二烯基化合物的研究 20060531 浙江省教育厅 2006-2008,1万 负责人

个人简历

学习、工作与生活经历:
1988.09 - 1992.07,山东建筑材料工业学院分析化学系,攻读学士学位。
1992.09 - 1995.07,中国科学院福建物质结构研究所,攻读硕士学位。
主要开展过渡金属配合物的设计、合成、与DNA作用机制、抗菌和抗肿瘤方面研究。
个人简历:
1995.09 - 1999.07,中国科学院福建物质结构研究所,工程师。
1999.7 - 2003.06, 新加坡国立大学化学系,攻读博士学位。
2003.10 - 2005.11, 美国贝勒大学化学系,博士后。
2005.12 - 2008.11,中国计量学院生命科学学院药学系,讲师。
2008. 11 - 至今,中国计量学院生命科学学院药学系,教授。

其他

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